Below is a list of projects applying open source principles to R&D for the COVID-19 crisis. Learn more about each initiative and contribute to the effort. Together, we seek to address the pandemic and leverage collaborative approaches.
LIST OF PROJECTS
Open Source COVID-19 Vaccine
Humanity’s urgent need for a vaccine, or set of vaccines, for SARS-CoV-2 needs no elaboration. Quite simply, this is one of the more pressing scientific/humanitarian needs of the century.
With the Harvard School of Medicine and the Government of India, we are close to launching multiple phase 3 COVID-19 vaccine trials. Through this venture, OpenVax, we seek to fight COVID-19 and future pandemics rapidly and equitably by repurposing existing widely-available off-patent low-cost vaccines with strong safety records.
With the European Vaccine Initiative (EVI), we are working to develop a computational platform to develop a COVID-19 vaccine.
Learn more about our ventures and take part in the fight.
Open Source COVID-19 Drugs: In Silico Drug Repurposing
This crowdsourcing for open source COVID-19 drug repurposing research project can be broken down into the following steps:
A. Crowdsource to build a systems biology model for the virus, and for drug target identification.
B. Virus target on host receptor (ACE2) modeling.
C. Host factors that can protect from the virus.
Project conceptualized by and mentored by Professor Samir K. Brahmachari.
OSP Idea Factory: C-19 Drug Discovery Hypotheses
This is a Massive Online Open Research (MOOR) initiative for COVID-19, a global collaborative research effort of the open source pharma community that seeks to tap into the minds of scientists and researchers across the world to virtually screen molecules to fight the virus. Through collective intelligence and open source approaches, we can support the rapid discovery of molecules and COVID-19 targets. Phase 1 of this project involves docking various molecules in the targets of COVID-19. We welcome all to contribute their hypotheses using the form below.
Global Repurposing Platform COVID-19
The outbreak of COVID-19, a new strain of coronavirus, emerged from Wuhan in late 2019, China and has spread globally ever since its outbreak. Currently, there is no definite treatment for COVID-19, although few therapeutics, such as small molecules, vaccines, antibodies are under investigation. The need of the hour is to come up with a treatment at the earliest possible. So our strategy is to look into FDA approved drugs that could be repurposed against COVID-19.
Towards this endeavour we are making a consolidated effort to bring on to the platform different resources available globally for repurposing FDA approved drugs for COVID. We will plug in a discussion forum on top of it, which would enable the participation of scientific/non-scientific communities from different parts of the globe.
If you have a project to suggest, please get in touch with firstname.lastname@example.org