PROJECTS
Below are a list of projects and initiatives conducted by OSPF teams around the world. For a list of our US-based projects , please see OSPF-USA.
Clinical Trials (OSPF-India)
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India Health Fund Open Source Clinical Trial Repurposing already-approved “off patent generic drugs” in order to rapidly and cost-effectively create new treatments and regimens against neglected infectious diseases, using open methodology conforming to standard regulatory endpoints. Future project. Funded by the India Health Fund. |
Metformin Clinical Trial A 3-center Phase 2b clinical trial of metformin, a generic diabetes drug, as an adjunct therapy for tuberculosis. Open IP, open data (once ready), and openly-available protocol published in open access academic journal. In partnership with the Government of India’s National Institute for Research in Tuberculosis (NIRT). CTRI site | More about the trial | Join the OSP Metformin-TB Facebook page |
Early Stage Drug Discovery (OSPF-India)
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Ayurvedic Research Accumulating and analyzing traditional health care systems with modern tools. |
Crowdsource Program for Neglected Disease Research An evolving project and discussion space for post graduates, researchers, and professional students who are passionate about solving problems in the health sector, particularly with a focus on neglected diseases |
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Generics Repurposing Database Project Enabling low cost generic drugs to be used for other diseases on an affordable basis. |
In Silico Research Peer-reviewed research papers have been published by members of the OSPF Bangalore scientific team and affiliated open researchers. View publications |
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Nipah Virus Response Conducting open source research to find possible cures for the fatal infection - for which there is currently no available treatment or vaccine. Learn more |
TB, Chikungunya, and Nipah Virus Knowledge Graph Building an open, living, AI-powered, automatically updated knowledge base and knowledge graph focused on the specific content needed to enable drug discovery and development for TB, Chikungunya, and Nipah Virus. US operations funded by Wellcome Trust, UK. TB Knowledge Graph in partnership with Mayo Clinic Center for Tuberculosis. OSPF has partnered with Ingentium, Inc., to provide interactive knowledgebases and knowledgegraphs for TB, Chikungunya, and Nipah Virus. An interactive dashboard which provides easy access to all tools and applications is available. |
Education and Awareness (OSPF-India and OSPF-USA)
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Global Conferences
TB Digital Quilt A collection of videos, displayed in the form of a quilt, contributed by people across the world sharing their thoughts and experiences concerning tuberculosis to raise awareness about TB and bring together community in support of those affected by the disease. www.tbdigitalquilt.org |
Lectures, Meetings, Workshops
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Tuberculosis Newsletters In collaboration with TBInfo and NIAS, we have created a series of newsletters dedicated to tuberculosis. This is a small initiative towards promoting awareness about tuberculosis that we hope will go a long way in helping end the disease and support the fight against current and future global pandemics. We would appreciate any thoughts or suggestions regarding this newsletter or the articles. Issue 1 (August 2020) Issue 2 (January 2021) Issue 3 (August 2021) |
Women Scientists Program
A series of workshops connecting women scientists through virtual labs and whittling down potential molecules that could eventually be turned into drugs to fight diseases, such as tuberculosis. View BBC News article
A series of workshops connecting women scientists through virtual labs and whittling down potential molecules that could eventually be turned into drugs to fight diseases, such as tuberculosis. View BBC News article
World TB Day 2018, NIAS, Bangalore
